Jordan holl ppt_1

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1. The Function of the DNAM-1 Receptor in Hepatitis C-induced Chronic Liver Inflammation Jordan Holl Laboratory of Dr. Shibuya University of Tsukuba 2. Known Information…
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  • 1. The Function of the DNAM-1 Receptor in Hepatitis C-induced Chronic Liver Inflammation Jordan Holl Laboratory of Dr. Shibuya University of Tsukuba
  • 2. Known Information • Hepatitis C – Liver inflammation • Cirrhosis of the Liver • Scarring • Cancer • DNAM-1 (CD226) – Elimination of intracellular pathogens via NK/T-cells – Viruses – Bacteria – Tumors
  • 3. Unknown Information • To discover the role of DNAM-1 in hepatitis C infection and its resulting inflammation and cirrhosis
  • 4. Methodology • Multiple mouse knockout strains + control • Monitor observable affects such as disease progression, symptoms, mortality, and immune cell activity.
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